Characterization of mixing in stirred tank bioreactors equipped with rushton turbines

Compartment Mixing Model in a Stirred Tank Equipped Dual Rushton Turbine

A Study on Liquid-liquid Mixing in a Stirred Tank with a 6-Blade Rushton Turbine

The turbulent flow field generated in a baffled stirred tank was computed by large eddy simulation (LED) and the flow field was developed using the Sliding Mesh (SM) approach. In this CFD study, mixing times and power number have been determined for a vessel agitated by a 6-blade Rushton turbine. The predicted results were compared with the published experimental data. The satisfactory results ...

Comparison of mixing between single- and bubbly two-phase systems in a Rushton stirred tank

Mixing is a widely practiced operation to effect distribution, intermingling and homogeneity of matter. Stirred tanks with different geometries (such as in main container tanks, impellers, baffles, etc.) are also widely used to mix different materials. The forces applied by impellers develop overall circulation or bulk flow. Superimposed on this flow pattern, there are turbulent eddies and also...

Adaptive Extremum Seeking Control of Continuous Stirred Tank Bioreactors

In this paper, we present an adaptive extremum seeking control scheme for continuous stirred tank bioreactors. The proposed adaptive extremum seeking approach utilizes the structure information of the kinetics of the bioreactors to construct a seeking algorithm that drives the system states to the desired set-points that extremize the value of an objective function. Lyapunov’s stability theorem...

Shear rate in stirred tank and bubble column bioreactors

Stirred tanks and bubble columns are widely used as mixing essels and bioreactors. Average spatial fluid velocity gradients t the level of the eddies or the prevailing shear rate, is an imporant variable in bioreactors but is not easy to characterize. A nowledge of shear rate is essential for at least two main reasons: 1) shear rate influences the average apparent viscosity of nonewtonian fluid...